Knockout ofDrosophilaRNase ZLimpairs mitochondrial transcript processing, respiration and cell cycle progression
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چکیده
منابع مشابه
Knockout of Drosophila RNase ZL impairs mitochondrial transcript processing, respiration and cell cycle progression
RNase Z(L) is a highly conserved tRNA 3'-end processing endoribonuclease. Similar to its mammalian counterpart, Drosophila RNase Z(L) (dRNaseZ) has a mitochondria targeting signal (MTS) flanked by two methionines at the N-terminus. Alternative translation initiation yields two protein forms: the long one is mitochondrial, and the short one may localize in the nucleus or cytosol. Here, we have g...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2015
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkv1149